| Date | Location | Result | |
| 03/21/19 | Wells Fargo Arena, Des Moines, Iowa | Minnesota 86, Louisville 76 | Box score |
| 03/14/19 | ACC Tournament, Charlotte, N.C. | North Carolina 83, Louisville 70 | Box score |
| 03/13/19 | ACC Tournament, Charlotte, N.C. | Louisville 75, Notre Dame 53 | Box score |
| 03/09/19 | John Paul Jones Arena, Charlottesville | Virginia 73, Louisville 68 | Box score |
| 03/03/19 | KFC Yum! Center, Louisville, Ky. | Louisville 75, Notre Dame 61 | Box score |
| 02/27/19 | Silvio O. Conte Forum, Boston, Mass. | Boston College 66, Louisville 59 | Box score |
| 02/23/19 | KFC Yum! Center, Louisville, Ky. | Virginia 64, Louisville 52 | Box score |
| 2/20/19 | Carrier Dome, Syracuse, N.Y. | Syracuse 69, Louisville 49 | Box score |
| 02/16/19 | KFC Yum! Center, Louisville, Ky. | Louisville 56, Clemson 55 | Box score |
| 02/12/19 | KFC Yum! Center, Louisville, Ky. | Duke 71, Louisville 69 | Box score |
| 02/09/19 | the Tucker Center - Tallahassee, FL | Florida State 80, Louisville 75 (OT) | Box score |
| 02/04/19 | Cassell Coliseum, Blacksburg, Va. | Louisville 72, Virginia Tech 64 | Box score |
| 02/02/19 | KFC Yum! Center, Louisville, Ky. | North Carolina 79, Louisville 69 | Box score |
| 01/30/19 | Lawrence Joel Veterans Memorial Coliseum | Louisville 82, Wake Forest 54 | Box score |
| 01/26/19 | KFC Yum! Center, Louisville, Ky. | Louisville 66, Pitt 51 | Box score |
| 01/24/19 | KFC Yum! Center, Louisville, Ky. | Louisville 84, NC State 77 | Box score |
| 01/19/19 | McCamish Pavilion, Atlanta, Ga. | Louisville 79, Georgia Tech 51 | Box score |
| 01/16/19 | KFC Yum! Center, Louisville, Ky. | Louisville 80, Boston College 70 | Box score |
| 01/12/19 | Smith Center, Chapel Hill, N.C. | Louisville 83, North Carolina 62 | Box score |
| 01/09/19 | Petersen Events Center (Pittsburgh, Pa.) | Pitt 89, Louisville 86 (OT) | Box score |
| 01/06/19 | KFC Yum! Center, Louisville, Ky. | Louisville 90, Miami 73 | Box score |
| 12/29/18 | KFC Yum! Center, Louisville, Ky. | Kentucky 71, Louisville 58 | Box score |
| 12/21/18 | KFC Yum! Center, Louisville, Ky. | Louisville 73, Robert Morris 59 | Box score |
| 12/15/18 | KFC Yum! Center, Louisville, Ky. | Louisville 83, Kent State 70 | Box score |
| 12/12/18 | KFC Yum! Center, Louisille, Ky. | Louisville 72, Lipscomb 68 | Box score |
| 12/08/18 | Assembly Hall (Bloomington, Ind.) | Indiana 68, Louisville 67 | Box score |
| 12/05/18 | KFC Yum! Center | Louisville 86, Central Arkansas 41 | Box score |
| 12/01/18 | Prudential Center, Newark, NJ | Louisville 70, Seton Hall 65 | Box score |
| 11/27/18 | KFC Yum! Center, Louisville, Ky. | Louisville 82, Michigan State 78 (OT) | Box score |
| 11/23/18 | Barclays Center - Brooklyn, N.Y. | Marquette 77, Louisville 74 (OT) | Box score |
| 11/21/18 | Brooklyn, N.Y. - Barclays Center | Tennessee 92, Louisville 81 | Box score |
| 11/16/18 | KFC Yum! Center, Louisville, Ky. | Louisville 86, Vermont 78 | Box score |
| 11/13/18 | KFC Yum! Center, Louisville, Ky. | Louisville 104, Southern U. 54 | Box score |
| 11/08/18 | KFC Yum! Center, Louisville, Ky. | Louisville 85, Nicholls St. 72 | Box score |