| Date | Location | Result | |
| 10-28-10 | Storrs, Conn. | CONNECTICUT 3, Louisville 0 | Box score |
| 10-24-10 | Piscataway, N.J. | Rutgers 3, Louisville 0 | Box score |
| 10-22-10 | South Orange, N.J. | Louisville 1, Seton Hall 0 | Box score |
| 10-17-10 | Milwaukee, Wis. | Marquette 4, Louisville 3 (OT) | Box score |
| 10-15-10 | Tampa, Fla. | USF 1, Louisville 0 | Box score |
| 10-10-10 | Louisville, Ky. | Georgetown 3, Louisville 1 | Box score |
| 10-08-10 | Louisville, Ky. | Louisville 5, Villanova 2 | Box score |
| 10-03-10 | Louisville, Ky. | West Virginia 2, Louisville 1 | Box score |
| 10-01-10 | Louisville, Ky. | Pittsburgh 2, Louisville 0 | Box score |
| 09-26-10 | Louisville, Ky. | Notre Dame 5, Louisville 0 | Box score |
| 09-24-10 | Chicago, Ill. | Louisville 2, DePaul 1 | Box score |
| 09-19-10 | Champaign, Ill. | Illinois 3, Louisville 0 | Box score |
| 09-16-10 | Louisville, Ky. | Louisville 3, Cincinnati 1 | Box score |
| 09-12-10 | St. Louis, Mo. | Louisville 2, Saint Louis 0 | Box score |
| 09-09-10 | Louisville, Ky. | Louisville 2, Kentucky 0 | Box score |
| 09-03-10 | Louisville, Ky. | Louisville 4, Toledo 1 | Box score |
| 08-29-10 | Columbia, S.C. | Louisville 2, Bucknell 0 | Box score |
| 08-27-10 | Columbia, S.C. | Louisville 1, South Carolina 0 | Box score |
| 08-20-10 | Louisville, Ky. | Louisville 4, Eastern Kentucky 1 | Box score |