| Date | Location | Result | |
| 3/17/10 | FREEDOM HALL, LOUISVILLE, KY | BRADLEY 69, LOUISVILLE 59 | Box score |
| 3/6/10 | XL Center Hartford, Conn. | NOTRE DAME 89, LOUISVILLE 52 | Box score |
| 3/5/10 | XL Center Hartford, Conn. | LOUISVILLE 79, PITTSBURGH 71 | Box score |
| 03/01/10 | Louis Brown Ath. Ctr. Piscataway, NJ | RUTGERS 72, LOUISVILLE 52 | Box score |
| 2/27/10 | FREEDOM HALL, LOUISVILLE, KY | USF 63, LOUISVILLE 60 | Box score |
| 02/24/10 | South Orange, N.J. - Walsh Gymnasium | LOUISVILLE 72, SETON HALL 49 | Box score |
| 2/16/10 | FREEDOM HALL, LOUISVILLE, KY | LOUISVILLE 77, MARQUETTE 61 | Box score |
| 02/14/10 | Petersen Events Center, Pittsburgh, PA | PITTSBURGH 72, LOUISVILLE 69 | Box score |
| 2/10/10 | QUEENS, N.Y., Carnesecca Arena | ST. JOHN'S 91, LOUISVILLE 56 | Box score |
| 2/7/2010 | FREEDOM HALL, LOUISVILLE, KY | CONNECTICUT 84, LOUISVILLE 38 | Box score |
| 2/2/10 | FREEDOM HALL, LOUISVILLE, KY | CINCINNATI 74, LOUISVILLE 68 (OT) | Box score |
| 1/30/10 | WVU Coliseum, Morgantown, W.Va. | WEST VIRGINIA 72, LOUISVILLE 66 | Box score |
| 1/26/10 | FREEDOM HALL, LOUISVILLE, KY | LOUISVILLE 53, VILLANOVA 50 | Box score |
| 1/23/10 | FREEDOM HALL, LOUISVILLE, KY | SYRACUSE 64, LOUISVILLE 58 | Box score |
| 1/19/10 | FREEDOM HALL, LOUISVILLE, KY | NOTRE DAME 78, LOUISVILLE 60 | Box score |
| 01/16/10 | Washington, D.C. (McDonough Arena) | GEORGETOWN 60, LOUISVILLE 56 | Box score |
| 1/9/10 | FREEDOM HALL, LOUISVILLE, KY | LOUISVILLE 67, PROVIDENCE 48 | Box score |
| 01-05-10 | McGrath Arena (Chicago, Ill.) | DE PAUL 76, LOUISVILLE 70 (OT) | Box score |
| 01/02/10 | Cincinnati, Ohio (Fifth Third Arena) | LOUISVILLE 63, CINCINNATI 49 | Box score |
| 12/29/09 | FREEDOM HALL, LOUISVILLE, KY | LOUISVILLE 91, IPFW 62 | Box score |
| 12/22/09 | Lundholm Gym | LOUISVILLE 76, NEW HAMPSHIRE 67 | Box score |
| 12/20/09 | Memorial Coliseum, Lexington, KY | KENTUCKY 101, LOUISVILLE 67 | Box score |
| 12/16/09 | Thompson-Boling Arena, Knoxville, Tenn. | TENNESSEE 86, LOUISVILLE 56 | Box score |
| 12/13/09 | FREEDOM HALL, LOUISVILLE, KY | LOUISVILLE 88, IUPUI 58 | Box score |
| 12/09/09 | Freedom Hall, Louisville, Ky. | MIDDLE TENNESSEE 94, LOUISVILLE 84 | Box score |
| 12/6/09 | FREEDOM HALL, LOUISVILLE, KY | LOUISVILLE 60, UTAH 55 | Box score |
| 12/02/09 | Mount Pleasant, Mich. (Rose Center) | CENTRAL MICHIGAN 84, LOUISVILLE 75 | Box score |
| 11/28/09 | Cancun, Mexico - Thanksgiving Classic | LOUISVILLE 82, OLD DOMINION 75 | Box score |
| 11/27/09 | Cancun, Mexico - Thanksgiving Classic | LOUISVILLE 81, NORTHERN IOWA 53 | Box score |
| 11/22/09 | FREEDOM HALL, LOUISVILLE, KY | LOUISVILLE 84, TENNESSEE TECH 54 | Box score |
| 11/17/09 | West Hartford, CT (Chase Arena) | HARTFORD 62, LOUISVILLE 50 | Box score |
| 11/15/09 | UD Arena | LOUISVILLE 65, DAYTON 63 | Box score |