| Date | Location | Result | |
| Dec 31, 2004 | Memphis, Tenn. | Louisville Cardinals 44, Boise State 40 | Box score |
| Dec 04, 2004 | New Orleans, La. | Louisville Cardinals 55, Tulane 7 | Box score |
| Nov 27, 2004 | Louisville, KY | Louisville Cardinals 70, Cincinnati 7 | Box score |
| Nov 20, 2004 | Houston, Texas | Louisville Cardinals 65, Houston 27 | Box score |
| Nov 10, 2004 | Louisville, KY | Louisville Cardinals 55, TCU 28 | Box score |
| Nov 04, 2004 | Memphis, Tenn. | Louisville Cardinals 56, MEMPHIS 49 | Box score |
| Oct 22, 2004 | Louisville, KY | Louisville Cardinals 41, South Florida 9 | Box score |
| Oct. 14,2004 | Miami, Fla. | UM 41, Louisville Cardinals 38 | Box score |
| Oct 02, 2004 | Louisville, KY | Louisville Cardinals 59, ECU 7 | Box score |
| Sep 25, 2004 | Chapel Hill, N.C. | Louisville Cardinals 34, North Carolina 0 | Box score |
| Sep 11, 2004 | WEST POINT, N.Y. | Louisville Cardinals 52, ARMY BLACK KNIGHTS 21 | Box score |
| Sep 05, 2004 | Louisville, KY | Louisville Cardinals 28, Kentucky 0 | Box score |