| Date | Location | Result | |
| 3/20/18 | KFC Yum! Center, Louisville, KY | Mississippi State 79, LOUISVILLE 56 | Box score |
| 3/18/18 | KFC Yum! Center, Louisville, KY | LOUISVILLE 84, Middle Tennessee 68 | Box score |
| 3/13/18 | KFC Yum! Center, Louisville, KY | LOUISVILLE 66, NORTHERN KENTUCKY 58 | Box score |
| 03/08/18 | Barclays Center (Brooklyn, NY) | Virginia 75, LOUISVILLE 58 | Box score |
| 03/07/18 | Barclays Center (Brooklyn, NY) | LOUISVILLE 82, Florida State 74 | Box score |
| 03/03/18 | Raleigh, N.C. (PNC Arena) | NC State 76, LOUISVILLE 69 | Box score |
| 3/1/18 | KFC Yum! Center, Louisville, KY | Virginia 67, LOUISVILLE 66 | Box score |
| 02/24/18 | Cassell Coliseum, Blacksburg, Va. | LOUISVILLE 75, Virginia Tech 68 | Box score |
| 02/21/18 | Cameron Indoor Stadium, Durham, N.C. | Duke 82, LOUISVILLE 56 | Box score |
| 2/17/18 | KFC Yum! Center, Louisville, KY | North Carolina 93, LOUISVILLE 76 | Box score |
| 2/11/18 | Petersen Events Center (Pittsburgh, Pa.) | LOUISVILLE 94, PITTSBURGH 60 | Box score |
| 2/8/18 | KFC Yum! Center, Louisville, KY | LOUISVILLE 77, Georgia Tech 54 | Box score |
| 2/5/18 | KFC Yum! Center, Louisville, KY | Syracuse 78, LOUISVILLE 73 | Box score |
| 2/3/18 | KFC Yum! Center, Louisville, KY | Florida State 80, LOUISVILLE 76 | Box score |
| 01/31/18 | Charlottesville, Va. (JPJ) | Virginia 74, LOUISVILLE 64 | Box score |
| 1/27/18 | KFC Yum! Center, Louisville, KY | LOUISVILLE 96, Wake Forest 77 | Box score |
| 01/24/18 | Coral Gables, Fla. (Watsco Center) | Miami 78, LOUISVILLE 75 (OT) | Box score |
| 1/21/18 | KFC Yum! Center, Louisville, KY | LOUISVILLE 77, Boston College 69 | Box score |
| 1/16/18 | Notre Dame, Ind. (Purcell Pavilion) | LOUISVILLE 82, Notre Dame 78 (2OT) | Box score |
| 1/13/18 | KFC Yum! Center, Louisville, KY | LOUISVILLE 94, Virginia Tech 86 | Box score |
| 01/10/18 | the Tucker Center - Tallahassee, FL | LOUISVILLE 73, Florida State 69 | Box score |
| 01/06/18 | Clemson, S.C. (Littlejohn Coliseum) | Clemson 74, LOUISVILLE 69 (OT) | Box score |
| 1/2/18 | KFC Yum! Center, Louisville, KY | LOUISVILLE 77, PITTSBURGH 51 | Box score |
| 12/29/17 | Rupp Arena - Lexington, KY | Kentucky 90, LOUISVILLE 61 | Box score |
| 12/23/17 | KFC Yum! Center, Louisville, KY | LOUISVILLE 74, GRAND CANYON 56 | Box score |
| 12/20/17 | KFC Yum! Center, Louisville,KY | LOUISVILLE 70, ALBANY 68 | Box score |
| 12/16/17 | Madison Square Garden, New York, NY | LOUISVILLE 81, MEMPHIS 72 | Box score |
| 12/11/17 | KFC Yum! Center, Louisville, KY | LOUISVILLE 102, BRYANT 59 | Box score |
| 12/9/17 | KFC Yum! Center, Louisville, KY | LOUISVILLE 71, INDIANA 62 | Box score |
| 12/6/17 | KFC Yum! Center, Louisville, KY | LOUISVILLE 86, SIENA 60 | Box score |
| 12/3/17 | KFC Yum! Center, Louisville, KY | SETON HALL 79, LOUISVILLE 77 | Box score |
| 11/28/17 | West Lafayette, Ind. / Mackey Arena | Purdue 66, LOUISVILLE 57 | Box score |
| 11/24/17 | KFC Yum! Center, Louisville, KY | LOUISVILLE 84, ST. FRANCIS 72 | Box score |
| 11/21/17 | KFC Yum! Center, Louisville, KY | LOUISVILLE 84, SIU 42 | Box score |
| 11/17/17 | KFC Yum! Center, Louisville, KY | LOUISVILLE 87, OMAHA 78 | Box score |
| 11/12/17 | KFC Yum! Center, Louisville, KY | LOUISVILLE 72, GEORGE MASON 61 | Box score |