| Date | Location | Result | |
| 06-07-10 | Louisville, Ky. | Vanderbilt 3, Louisville Cardinals 2 | Box score |
| 06-06-10 | Louisville, Ky. | Vanderbilt 7, Louisville Cardinals 0 | Box score |
| 06-05-10 | Louisville, Ky. | Louisville Cardinals 7, Vanderbilt 1 | Box score |
| 06-04-10 | Louisville, Ky. | Louisville Cardinals 11, Saint Louis 2 | Box score |
| 05-29-10 | Clearwater, Fla. | St. John's Red Storm 5, Louisville Cardinals 3 | Box score |
| 05-28-10 | Clearwater, Fla. | Louisville Cardinals 9, USF 7 | Box score |
| 05-27-10 | Clearwater, Fla. | St. John's Red Storm 6, Louisville Cardinals 5 | Box score |
| 05-26-10 | Clearwater, Fla. | Louisville Cardinals 11, West Virginia 4 | Box score |
| 05-22-10 | Notre Dame, Ind. | Louisville Cardinals 13, Notre Dame 3 | Box score |
| 05-22-10 | Notre Dame, Ind. | Louisville Cardinals 4, Notre Dame 3 | Box score |
| 05-20-10 | Notre Dame, Ind. | Louisville Cardinals 6, Notre Dame 3 | Box score |
| 05-18-10 | Louisville, Ky. | Louisville Cardinals 14, Eastern Kentucky 3 | Box score |
| 05-16-10 | Louisville, Ky. | Louisville Cardinals 8, St. John's Red Storm 4 | Box score |
| 05-15-10 | Louisville, Ky. | Louisville Cardinals 10, St. John's Red Storm 6 | Box score |
| 05-14-10 | Louisville, Ky. | St. John's Red Storm 8, Louisville Cardinals 5 | Box score |
| 05-11-10 | Nashville, Tenn. | Vanderbilt 11, Louisville Cardinals 10 | Box score |
| 05-09-10 | Bethesda, Md. | Louisville Cardinals 10, Georgetown Hoyas 3 | Box score |
| 05-08-10 | Bethesda, Md. | Georgetown Hoyas 2, Louisville Cardinals 1 | Box score |
| 05-07-10 | Bethesda, Md. | Louisville Cardinals 5, Georgetown Hoyas 0 | Box score |
| 05-05-10 | Columbus, Ohio | Louisville Cardinals 10, Ohio State Buckeyes 8 | Box score |
| 05-04-10 | Columbus, Ohio | Louisville Cardinals 6, Ohio State Buckeyes 0 | Box score |
| 05-01-10 | Louisville, Ky. | Louisville Cardinals 24, Rutgers 6 | Box score |
| 04-30-10 | Louisville, Ky. | Louisville Cardinals 9, Rutgers 4 | Box score |
| 04-30-10 | Louisville, Ky. | Louisville Cardinals 5, Rutgers 3 | Box score |
| 04-28-10 | Louisville, Ky. | Louisville Cardinals 10, Kentucky Wildcats 9 | Box score |
| 04-25-10 | Louisville, Ky. | Seton Hall Pirates 8, Louisville Cardinals 6 | Box score |
| 04-24-10 | Louisville, Ky. | Louisville Cardinals 3, Seton Hall Pirates 1 | Box score |
| 04-23-10 | Louisville, Ky. | Louisville Cardinals 4, Seton Hall Pirates 2 | Box score |
| 04-21-10 | Louisville, Ky. | Louisville Cardinals 7, Western Kentucky 4 | Box score |
| 04-18-10 | Morgantown, W.Va. | Louisville Cardinals 10, West Virginia 1 | Box score |
| 04-17-10 | Morgantown, W.Va. | Louisville Cardinals 12, West Virginia 9 | Box score |
| 04-17-10 | Morgantown, W.Va. | Louisville Cardinals 8, West Virginia 1 | Box score |
| 04-14-10 | Bowling Green, Ky. | Louisville Cardinals 7, Western Kentucky 6 | Box score |
| 04-11-10 | Pittsburgh, Pa | Louisville Cardinals 9, Pittsburgh Panthers 7 | Box score |
| 04-10-10 | Pittsburgh, Pa. | Pittsburgh Panthers 15, Louisville Cardinals 5 | Box score |
| 04-09-10 | Pittsburgh, Pa. | Pittsburgh Panthers 8, Louisville Cardinals 3 | Box score |
| 04-06-10 | Lexington, Ky. | Kentucky Wildcats 5, Louisville Cardinals 0 | Box score |
| 04-03-10 | Louisville, Ky. | Louisville Cardinals 10, Villanova Wildcats 6 | Box score |
| 04-02-10 | Louisville, Ky. | Louisville Cardinals 7, Villanova Wildcats 0 | Box score |
| 04-01-10 | Louisville, Ky. | Louisville Cardinals 12, Villanova Wildcats 4 | Box score |
| 03-30-10 | Bloomington, Ind. | Louisville Cardinals 5, Indiana Hoosiers 4 | Box score |
| 03-27-10 | Louisville, Ky. | Connecticut Huskies 6, Louisville Cardinals 3 | Box score |
| 03-27-10 | Louisville, Ky. | Louisville Cardinals 4, Connecticut Huskies 2 | Box score |
| 03-26-10 | Louisville, Ky. | Louisville Cardinals 1, Connecticut Huskies 0 | Box score |
| 03-23-10 | Evansville, Ind. | Louisville Cardinals 8, Evansville 7 | Box score |
| 03-20-10 | Louisville, Ky. | Ball State Cardinals 5, Louisville Cardinals 1 | Box score |
| 03-20-10 | Louisville, Ky. | Louisville Cardinals 8, Ball State Cardinals 3 | Box score |
| 03-19-10 | Louisville, Ky. | Louisville Cardinals 11, Ball State Cardinals 7 | Box score |
| 03-16-10 | Louisville, Ky. | Louisville Cardinals 7, Xavier Musketeers 4 | Box score |
| 03-14-10 | Oxford, Miss. | Louisville Cardinals 10, Ole Miss Rebels 8 | Box score |
| 03-13-10 | Oxford, Miss. | Ole Miss Rebels 8, Louisville Cardinals 3 | Box score |
| 03-12-10 | Oxford, Miss. | Louisville Cardinals 6, Ole Miss Rebels 1 | Box score |
| 03-09-10 | Louisville, Ky. | Louisville Cardinals 9, Indiana Hoosiers 7 | Box score |
| 03-07-10 | Louisville, Ky. | Louisville Cardinals 12, Le Moyne Dolphins 1 | Box score |
| 03-06-10 | Louisville, Ky. | Louisville Cardinals 6, Le Moyne Dolphins 5 | Box score |
| 03-05-10 | Louisville, Ky. | Louisville Cardinals 8, Le Moyne Dolphins 1 | Box score |
| 03-03-10 | Louisville, Ky. | Louisville Cardinals 13, Evansville 6 | Box score |
| 02-28-10 | St. Petersburg, Fla. | Louisville Cardinals 5, Minnesota 4 | Box score |
| 02-27-10 | Clearwater, Fla. | Louisville Cardinals 17, Michigan State 6 | Box score |
| 02-26-10 | Dunedin, Fla. | Louisville Cardinals 2, Michigan Wolverines 0 | Box score |
| 02-23-10 | Louisville, Ky. | Louisville Cardinals 7, Morehead State 2 | Box score |
| 02-20-10 | Louisville, Ky. | Louisville Cardinals 8, Bowling Green State 7 | Box score |
| 02-20-10 | Louisville, Ky. | Louisville Cardinals 5, Bowling Green State 2 | Box score |
| 02-19-10 | Louisville, Ky. | Louisville Cardinals 13, Bowling Green State 1 | Box score |